Neurogenesis相关论文
目的:探究柴胡疏肝散(Chaihu-Shugan San,CSS)对慢性不可预知性温和应激(chronic unpredictable mild stress,CUMS)致抑郁小鼠行为及......
目的:探讨早期母爱剥夺对青春期(6~7周龄)大鼠抑郁样行为及海马区颗粒层神经发生的影响。方法:采用随机数字表法将新生大鼠根据窝......
The molecular, electrophysiological, and structural changes in the vestibular nucleus during vestibu
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Transplantation of neural stem cells overexpressing glial cell line-derived neurotrophic factor enha
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Detection and functional annotation of misregulated microRNAs in the brain of the Ts65Dn mouse model
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目的通过电针刺激慢性脑低灌注模型大鼠百会穴和大椎穴,观察海马组织头蛋白(Noggin)mRNA的表达,以及电针对慢性脑低灌注模型大鼠学习......
The details of adult neurogenesis, including environmental triggers, region specificity, and species ho-mology remain an......
目的越来越多的研究表明Eph/ephrin信号通路与成年脑损伤后神经发生有关,因此该文将对Eph/ephrin的结构及表达和各亚型间的相互作用......
目的探讨Src信号通路在室管膜下区(subventricular zone,SVZ)表达胆碱乙酰基转移酶(choline acetyltransferase,ChAT)的胆碱能神经元......
目的探讨多奈哌齐对脑梗死后室管膜下区(subventricular zone,SVZ)神经发生相关神经营养因子表达的影响。方法成年雄性昆明小鼠78只......
目的探讨丘脑前核(anterior thalamic nucleus,ANT)电刺激对颞叶癫痫大鼠海马神经元再生作用的影响。方法将32只雄性SD大鼠随机分为......
脑损伤是一个广义的概念,它包括外伤性、出血性、缺血性等各种原因引起的腩损伤.对于脑损伤的基础和临床研究目前主要集中在脑保护......
Adenovirus-mediated hypoxia-inducible factor-1 alpha gene transfer induces angiogenesis and neurogen
BACKGROUND: Hypoxia-inducible factor-1 (HIF-1) accumulates under conditions of hypoxia. HIF-1α target genes have pleiot......
Effects of primary microglia and astrocytes on neural stem cells in in vitro and in vivo models of i
Transplantation of neural stem cells(NSCs)can protect neurons in animal stroke models;however,their low rates of surviva......
Entacapone, a catechol-O-methyltransferase inhibitor, can strengthen the therapeutic effects of levodopa on the treatmen......
Hydrogen sulfide (H2S) is regarded to be a protectant against diseases of the central nervous system and cardiovascular ......
Microglia are brain-resident immune cells that contribute to the maintenance of brain homeostasis. In the epileptic brai......
Obesity is a multifactorial disease that is the conc of human societies[1]. Obesity is the cause of many diseases such a......
Emerging evidence indicates that pentraxin 3 is an acute-phase protein that is linked with the immune response to inflam......
Insulin-like growth factor 1 partially rescues early developmental defects caused by SHANK2 knockdow
SHANK2 is a scaffold protein that serves as a protein anchor at the postsynaptic density in neurons. Genetic variants of......
MicroRNA-124 slows down the progression of Huntington’s disease by promoting neurogenesis in the str
MicroRNA-124 contributes to neurogenesis through regulating its targets, but its expression both in the brain of Hunting......
Several experimental therapeutics have been demonstrated to be safe and effective in animal models of neurological disor......
Nicotinamide mononucleotide adenylyltransferase 1 gene NMNAT1 regulates neuronal dendrite and axon m
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Functional electrical stimulation increases neural stem/progenitor cell proliferation and neurogenes
Background Functional electrical stimulation (FES) is known to promote the recovery of motor function in rats with ische......
Detection and functional annotation of misregulated microRNAs in the brain of the Ts65Dn mouse model
Background Brain hypoplasia and mental retardation in Down syndrome (DS) can be attributed to a severe and selective dis......
Hippophae rhamnoides L.leaves extract enhances cell proliferation and neuroblast differentiation thr
Background Hippophae rhamnoides L.(HL) exerts antioxidant activities against various oxidative stress conditions.In this......
Active Compounds and Molecular Targets of Chinese Herbal Medicine for Neurogenesis in Stroke Treatme
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
帕金森病(PD)动物模型对理解该病病因、发病机制以及检测新的治疗方案具有重要作用。成年哺乳动物脑中内源性神经增生的发现为基于......
Neurogenesis by Activation of Inherent Neural Stem Cells in the Rat Hippocampus after Cerebral Infar
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Results from the present study demonstrated that transplantation of autologous bone marrow-derived mesenchymal stem cell......
The cerebral cortical expansion index refers to the ratio between left and right cortex width and is recognized as an in......
Length and thickness of 152 corpus cal osa were measured in neonates within 24 hours of birth. Using ultrasonic diagnost......
The adult brain has been thought traditionally as a structure with a very limited regenerative capacity. It is now evide......
Maternal alcohol consumption during pregnancy has detrimental effects on fetal central nervous system development. Mater......
Objective To explore the effect of Ligustrazine on neurogenesis in cortex after focal cerebral ischemia in rats. Methods......
Objective To investigate the proliferative response and time course of endogenous neural stem/progenitor cells after cer......
Short-term environmental enrichment exposure induces proliferation and maturation of doublecortin-po
Previous studies have demonstrated that doublecortin-positive immature neurons exist pre-dominantly in the superficial l......
背景 近年的研究显示γ-氧基丁酸(γ-aminobutyric acid,GABA)-GABAA受体通路与神经发生有密切联系.神经发生不仅存在于胎儿期和......
Notch基因首先由Metz等发现,后因证实该基因功能缺失的果蝇其翅膀边缘会造成一些缺刻表型而得名.研究表明,Notch是一个高度保守的......
神经发生是指神经干细胞自我增殖和分化成为新的神经元,并整合入神经网络的生物学过程,包括胚胎时期神经发牛和成体时期的神经发生......
Paravertebral fascial massage promotes brain development of neonatal rats via the insulin-like growt
Massage in traditional Chinese medicine can promote body and brain development of premature and normal newborn infants. ......
脑缺血后神经发生是神经科学领域的研究热点之一.文章主要从脑缺血后神经发生的主要过程、调节因子、信号通路、微环境以及如何促......
目的 探讨电刺激嗅球对脑室下区(SVZ)神经干细胞(NSC)增殖、迁移及其分化的影响.方法 取SD大鼠48只,随机分为正常对照组、假刺激组......
目的 研究条件恐惧刺激后大鼠海马内新生神经细胞的表达变化,探讨恐惧情绪性记忆的神经牛物学机制.方法 24只成年雄性大鼠随机分成......